Ryan Reynolds: Wade Wilson, Deadpool

Josh Brolin: Cable

Morena Baccarin: Vanessa

Julian Dennison: Firefist

Zazie Beetz: Domino

T.J. Miller: Weasel

Leslie Uggams: Blind Al

Karan Soni: Dopinder

Brianna Hildebrand: Negasonic Teenage Warhead

Eddie Marsan: Headmaster

Shioli Kutsuna: Yukio