Simu Liu: Shaun, Shang-Chi

Tony Chiu-Wai Leung: Xu Wenwu

Awkwafina: Katy

Ben Kingsley: Trevor Slattery

Meng'er Zhang: Xialing

Fala Chen: Li

Michelle Yeoh: Ying Nan

Wah Yuen: Master Guang Bo

Florian Munteanu: Razor Fist

Andy Le: Death Dealer

Paul W. He: Chancellor Hui

Jayden Zhang: Young Shang-Chi

Elodie Fong: Young Xialing

Arnold Sun: Teen Shang-Chi