Michael Rooker: Savant

Viola Davis: Amanda Waller

John Ostrander: Doctor Fitzgibbon

Joel Kinnaman: Colonel Rick Flag

Nathan Fillion: T.D.K.

Jai Courtney: Captain Boomerang

Flula Borg: Javelin

Mayling Ng: Mongal

Pete Davidson: Blackguard

Sean Gunn: Weasel, Calendar Man

Margot Robbie: Harley Quinn

Stephen Blackehart: Briscoe

Steve Agee: John Economos, On-Set King Shark

Tinashe Kajese: Flo Crawley