Superman/Clark Kent : Brandon Routh

Lois Lane : Kate Bosworth

Lex Luthor : Kevin Spacey
Jimmy Olsen: Sam Huntington
Perry White: Frank Langella

Martha Kent: Eva Marie Saint

Jor-El: Marlon Brando (archive)

Richard White: James Marsden

Kitty Kowalski: Parker Posey

Bo the Bartender: Jack Larson

Gertrude Vanderworth: Noel Neill